Assessing good laboratory practices (GLP)

Three authorities are responsible for checking the conformity of studies with GLP principles and the test facilities in which they are carried out, according to the nature of the chemical product:

• Inspecting the application of GLP principles for tests on medicinal products for human use, cosmetic products and tattooing products is the remit of the French national agency for medicines and health products safety (ANSM - Agence nationale de sécurité du médicament et des produits de santé).
• Inspecting the application of these principles for tests on veterinary medicines and similar products is the remit of the French national agency for food, environmental and occupational health and safety (ANSES - Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail), and more specifically of the National agency for veterinary medical products (ANMV - Agence nationale du médicament vétérinaire), a branch of the ANSES.
• Cofrac controls the GLP conformity of test facilities located on French territory for tests on pesticides, additives for human and animal food, as well as on industrial chemicals. It examines the applications and monitors the files of any test facility declaring to apply the principles of GLP, organizes the inspections and ensures the recruitment of assessors and technical experts who carry them out. Cofrac takes decisions relating to GLP conformity on behalf of the State.